Clinical research - Clinical Study

Recruitment status: Free to join the group

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Research drugs: NCT06452277: SOHO-02 Research

香港聯合腫瘤中心非小細胞肺癌臨床研究 NCT06452277 招募志願者
The United Cancer Center of Hong Kong is conducting a clinical study of NCT06452277, recruiting patients with advanced non-small cell lung cancer (NSCLC) with HER2 gene mutations to participate, using BAY 2927088 or Pembrolizumab in combination with chemotherapy.

Recruitment of clinical research volunteers (lung cancer)

The Hong Kong United Oncology Centre is currently conducting an international Phase III clinical trial. If you are a patient with advanced non-small cell lung cancer (NSCLC) with a human epidermal growth factor receptor 2 (HER2) gene mutation, please contact us. We will conduct an initial assessment to determine your eligibility for this clinical trial. Drug and imaging scans are free of charge. However, patients must understand the purpose of the study and any potential risks.

Research name

A study to further compare the efficacy and safety of BAY 2927088 and standard therapy in participants with advanced non-small cell lung cancer (NSCLC) with mutations in the human epidermal growth factor receptor 2 (HER2) gene

A Phase 3 open-label, randomized, active-controlled, multicenter trial to evaluate the efficacy and safety of orally administered BAY 2927088 compared with standard of care as a first-line therapy in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) with HER2-activating mutations.

ClinicalTrials.gov Identifier: NCT06452277 (View detailed trial information)

Patient eligibility

  • Patients with advanced non-small cell lung cancer (NSCLC) with mutations in the human epidermal growth factor receptor 2 (HER2) gene

Research remuneration

  • Related treatment drugs, image scans and doctor's consultations are free of charge

Research process

If you are eligible to participate in this study, you will be treated with BAY 2927088 or Pembrolizumab plus chemotherapy (i.e. Pemetrexed and Carboplatin/Cisplatin) until the end of treatment or your condition worsens.

Related risks

During the study period, you may experience discomfort and risk due to treatment with BAY 2927088 or Pembrolizumab plus chemotherapy (i.e. Pemetrexed and Carboplatin/Cisplatin). Discomfort and risk may vary from person to person.

Contact method

Interested participants can contact us through the following methods for further understanding:

Related resources

Inquire about more research projects:Clinical Research Page of the United Cancer Centre of Hong Kong

Learn more about non-small cell lung cancer:Hong Kong Hospital Authority-Lung Cancer Information

Research sponsor

Bayer

Find out more about cancer treatment

Treatment method

Related cancer types