香港聯合腫瘤中心 (Hong Kong United Oncology Centre) 現正進行一項國際性的第三期臨床研究。假如您是高風險早期三陰性乳癌 (TNBC) 或荷爾蒙受體弱陽性／HER2 陰性乳癌患者，請和我們聯絡。我們會作初步評估，以決定能否滿足進入該項臨床研究的條件。藥物及影像掃瞄費用全免。然而，患者必需了解研究的目的及有機會帶來的潛在風險。
A Phase 3, Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer.
If eligible, you will be randomized 1:1 to receive MK-2870 plus pembrolizumab followed by standard chemotherapy plus pembrolizumab, or standard chemotherapy plus pembrolizumab (neoadjuvant), then surgery and adjuvant pembrolizumab, or pembrolizumab plus one optional adjuvant therapy.
Study drugs/procedures may cause mild-to-moderate discomfort. Actual experience varies. The study team will monitor closely and manage appropriately. Full details are in the informed consent and will be explained by the study physicians.
